In a study published in the US National Library of Medicine National Institutes of Health, loss of sleep and how it increases the risk factor for insulin resistance was further analysed.
The study noted: “Although sleep exerts marked modulatory effects on glucose metabolism, and molecular mechanisms for the interaction between sleeping and feeding have been documented, the potential impact of recurrent sleep curtailment on the risk for diabetes and obesity has only recently been investigated.
“In laboratory studies of healthy young adults submitted to recurrent partial sleep restriction, marked alterations in glucose metabolism including decreased glucose tolerance and insulin sensitivity have been demonstrated.
“The neuroendocrine regulation of appetite was also affected as the levels of the anorexigenic hormone leptin were decreased, whereas the levels of the orexigenic factor ghrelin were increased.
“Importantly, these neuroendocrine abnormalities were correlated with increased hunger and appetite, which may lead to overeating and weight gain.”
The study concluded that chronic sleep loss is a risk factor for weight gain, insulin resistance, and type 2 diabetes.”