Human dopamine transporter structure with cocaine revealed, unlocking addiction insights

Human dopamine transporter structure with cocaine revealed, unlocking addiction insights

In a recent study published in the journal Nature, researchers presented the molecular structure of dopamine transporter (DAT) complexed with cocaine. Cocaine is highly addictive, and its misuse can exacerbate psychiatric disorders. Although it exerts effects by binding to monoamine transporters, its inhibition of DAT underlies its addictive and rewarding properties. Currently, there are no …

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Many young adults who began vaping as teens can’t shake the habit

Many young adults who began vaping as teens can’t shake the habit

G Kumar’s vaping addiction peaked in college at the University of Colorado, when flavored, disposable vapes were taking off. “I’d go through, let’s say, 1,200 puffs in a week,” Kumar said. Vaping became a crutch for them. Like losing a cellphone, losing a vape pen would set off a mad scramble. “It needs to be …

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Healing the Wounds: Understanding the Connection Between Trauma and Addiction

Healing the Wounds: Understanding the Connection Between Trauma and Addiction

A full comprehension of the intricate correlation between trauma and addiction is crucial for efficacious therapy. Addiction is often misinterpreted as a series of bad choices, rather than a complex interplay between trauma and coping mechanisms. “What causes addiction?”, is one of the most deeply explored and researched questions. Why would someone persistently engage in …

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Inside the UK’s battle with pregabalin: How addiction fears over opioids and benzos left country sleepwalking towards unfolding fiasco with ‘Valium on steroids’

Inside the UK’s battle with pregabalin: How addiction fears over opioids and benzos left country sleepwalking towards unfolding fiasco with ‘Valium on steroids’

By Emily Stearn, Health Reporter and Stephen Matthews Health Editor For Mailonline 17:52 04 Mar 2024, updated 21:41 04 Mar 2024 Mounting fears over opioids and benzodiazepines have seen doctors increasingly dole out a supposedly ‘safer’ painkiller to Brits battling anxiety, epilepsy and nerve pain. Yet evidence now suggests pregabalin, widely thought to be less …

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Cannabis Use Linked to Higher Anxiety Disorder Risk

Cannabis Use Linked to Higher Anxiety Disorder Risk

Summary: A comprehensive study found a significant association between emergency department visits for cannabis use and the development of new anxiety disorders. Analyzing health data from over 12 million Ontarians, the research revealed that individuals who sought emergency care for cannabis use exhibited a nearly fourfold increase in the risk of being diagnosed with an …

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