Human dopamine transporter structure with cocaine revealed, unlocking addiction insights
In a recent study published in the journal Nature, researchers presented the molecular structure of dopamine transporter (DAT) complexed with cocaine. Cocaine is highly addictive, and its misuse can exacerbate psychiatric disorders. Although it exerts effects by binding to monoamine transporters, its inhibition of DAT underlies its addictive and rewarding properties. Currently, there are no …