Researchers overturn the prevailing theory for colorectal tumor initiation

Researchers overturn the prevailing theory for colorectal tumor initiation

Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer-causing genetic alterations appear. The results, published on May 29 in Developmental Cell, overturn the prevailing theory for colorectal tumor initiation and suggest new ways to diagnose the disease before it has …

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MUTYH gene mutation linked to increased risk of various solid tumors

Researchers overturn the prevailing theory for colorectal tumor initiation

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.  Since the early 2000s, scientists have known that …

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New sprayable gel promises safer endoscopic surgeries

New sprayable gel promises safer endoscopic surgeries

More than 20 million Americans undergo colonoscopy screenings every year, and in many of those cases, doctors end up removing polyps that are 2 cm or larger and require additional care. This procedure has greatly reduced the overall incidence of colon cancer, but not without complications, as patients may experience gastrointestinal bleeding both during and …

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Boosting fitness levels linked to lower prostate cancer risk

Boosting fitness levels linked to lower prostate cancer risk

In a recent study published in the British Journal of Sports Medicine, researchers investigate the relationship between changes in adult cardiorespiratory fitness (CRF) and the incidence and mortality of prostate cancer. Study: Association between change in cardiorespiratory fitness and prostate cancer incidence and mortality in 57,652 Swedish men. Image Credit: Peakstock / Shutterstock.com Background  In contrast to …

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Nutrition’s Narrow Line: Exploring the Diet-Cancer Link

Nutrition’s Narrow Line: Exploring the Diet-Cancer Link

A new study reveals how dietary folate enhances colon cancer risk in an animal model, emphasizing the need for cautious folate food fortification. This research uncovers a direct link between diet and colon cancer through epigenetic mechanisms, specifically DNA methylation. The findings are significant in understanding environmental influences on cancer risk and open new avenues …

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