Bladder cancer is currently treated in its earlier stages by localized intravesical chemotherapy or immunotherapy after removing the tumor. However, recurrences occur in up to 70% of patients at 5 years, while up to 30% fail to respond. This means a constant need to monitor and retreat these patients, driving costs sky-high for the treatment …
Psychotherapy is an effective treatment for adults with post-traumatic stress disorder (PTSD) following exposure to multiple traumatic events, according to new research from the University of East Anglia. The efficacy of psychotherapeutic interventions, or talking therapies, for treating PTSD in adults has been well-documented in various studies. However, until now, it had not been established …
In a recent study published in the journal Nature, researchers developed and tested a novel dry powder aerosol vaccine against COVID-19. The nanoparticle-based vaccine comprises cholera toxin B subunits with the SARS-CoV-2 RBD antigens. Study findings revealed that this single-use nasal spray promotes the robust production of IgG and IgA antibodies and bolsters local T …
A new study published in The Lancet Oncology discusses the efficacy of anastrozole, a molecule used to prevent breast cancer in postmenopausal women with a high risk of breast cancer. Study: Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of …
Scientists have conducted a systematic review and meta-analysis to compare the effectiveness of paracetamol and ibuprofen in treating episodic tension-type headaches. The research paper is published in the journal Scientific Reports. Study: Paracetamol versus ibuprofen in treating episodic tension-type headache: a systematic review and network meta-analysis. Image Credit: Artem Furman / Shutterstock Background Tension-type headache is the …
In a recent article published in Npj Vaccines, researchers describe how vaccination with recombinant zoster vaccine (RZV) could help prevent Herpes Zoster (HZ) infection (or shingles) and support healthy aging. Study: Healthy ageing: Herpes zoster infection and the role of zoster vaccination. Image Credit: BaLL LunLa/Shutterstock.com Background Reactivation of the varicella-zoster virus (VZV) due to declining immunity causes HZ, a …
For sickle cell disease (SCD), hydroxyurea is an established treatment. Despite this, hydroxyurea remains underutilized. New disease-modifying treatments (DMTs), namely, crizanlizumab, L-glutamine, and voxelotor, have recently been approved. A new JAMA Network Open study delved deeper into understanding the uptake of these DMTs in the context of current treatment strategies. Study: Use of Disease-Modifying Treatments in Patients With …
In a recent study published in Scientific Reports, researchers investigated the immunogenicity, safety, and effectiveness of Aripo-Zika (ARPV/ZIKV), a chimeric insect-specific flavivirus (ISFV)-Zika vaccine. Study: Exploring the immunogenicity of an insect-specific virus vectored Zika vaccine candidate. Image Credit: nechaevkon/Shutterstock.com Background The Zika virus (ZIKV) is a worldwide health issue; however, there are no Food and Drug Administration …