A major challenge in developing a vaccine for HIV is that the virus mutates fast-;very fast. Although a person initially becomes infected with one or a few HIV strains, the virus replicates and mutates quickly, resulting in a “swarm” of viral strains existing in a single body. But scientists at Scripps Research; IAVI; the Ragon …
A recent Science Immunology study revealed that neonatal gut bacteria produce serotonin and down-regulate monoamine oxidase A (MOA) to limit serotonin breakdown, thereby promoting immune tolerance. Study: Gut bacteria–derived serotonin promotes immune tolerance in early life. Image Credit: Tatiana Shepeleva/Shutterstock.com Background Bacterial colonization in the neonatal gut plays a crucial role in the development of the immune …
Scientists have long believed that a newborn’s immune system was an immature version of an adult’s, but new research from Cornell University shows that newborns’ T cells – white blood cells that protect from disease – outperform those of adults at fighting off numerous infections. These results help clarify why adults and infants respond differently …
Across the globe, more than 39 million people are living with the Human Immunodeficiency Virus (HIV), the virus that causes AIDS, including more than 1.3 million new HIV diagnoses last year. The majority of those afflicted -; approximately 76% -; have access to antiviral therapy that allows them to live with HIV as a chronic …
Evaluation of probiotic bacteria against WSSV Shrimps submerged with 100X L. johnsonii KD1 were significantly protected against WSSV, starting at 3 days post infection (dpi.) and more evident at 4 dpi., as shrimp mortality was lower than that of shrimps receiving 1X L. johnsonii KD1 and shrimps not receiving any probiotics (positive control) (Fig. 1A). This was consistent with …
Newswise — Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA that causes this to occur and found a way to prevent ‘off-target’ immune responses to enable the safer design of future mRNA therapeutics. …
The unprecedented coronavirus disease 2019 (COVID-19) pandemic facilitated the rapid development and subsequent deployment of several novel and highly effective vaccines. However, the role of antiviral treatments remained pivotal, especially for certain patient populations incapable of mounting an effective vaccine response or those reluctant to be vaccinated. In a recent review published in the journal Cellular …
Stand Up To Cancer® (SU2C) today announced three Research Teams focused on bringing new therapies to clinical trials for the treatment of gastroesophageal cancer (GEC). The Research Teams, a part of a Dream Team Collective supported by the Torrey Coast Foundation, will unite top researchers from 11 institutions to address critical problems in GEC prevention, …