Individual sleep need is flexible and dynamically related to cognitive function

Individual sleep need is flexible and dynamically related to cognitive function

Hirshkowitz, M. et al. National Sleep Foundation’s updated sleep duration recommendations: final report. Sleep Health 1, 233–243 (2015). Article  PubMed  Google Scholar  Watson, N. F. et al. Recommended amount of sleep for a healthy adult: a joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. Sleep 38, 843–844 (2015). PubMed  …

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High-resolution structure and biochemical properties of the LH1–RC photocomplex from the model purple sulfur bacterium, Allochromatium vinosum

High-resolution structure and biochemical properties of the LH1–RC photocomplex from the model purple sulfur bacterium, Allochromatium vinosum

Brune, D. C. Sulfur compounds as photosynthetic electron donors. in Anoxygenic Photosynthetic Bacteria (eds Blankenship, R. E., Madigan, M. T. & Bauer, C. E.) 847–870 (Kluwer Academic Publishers, Dordrecht, The Netherlands, 1995). Weissgerber, T. et al. Genome-wide transcriptional profiling of the purpler sulfur bacterium Allochromatium vinosum DSM 180T during growth on different reduced sulfur compounds. …

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Research reveals how jellyfish regenerate functional tentacles in days

Research reveals how jellyfish regenerate functional tentacles in days

ANI | Updated: Dec 28, 2023 21:22 IST Washington DC [US], December 28 (ANI): Cladonema, a jellyfish about the size of a pinkie nail, can regenerate an amputated tentacle in two to three days – but how? Across animals, including salamanders and insects, regenerating functional tissue is dependent on the ability to generate a blastema, …

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Unveiling prostate cancer’s Achilles’ heel

Unveiling prostate cancer’s Achilles’ heel

Researchers uncover a potential strategy to target and inhibit the androgen receptor in aggressive prostate cancer by exploiting protein droplets. An international research team, including experts from IRB Barcelona, Max Planck Institute for Molecular Genetics, and BC Cancer, discovered a potential method to target the androgen receptor, a significant factor in prostate cancer, through its …

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Gene mining and genomics-assisted breeding empowered by the pangenome of tea plant Camellia sinensis

Gene mining and genomics-assisted breeding empowered by the pangenome of tea plant Camellia sinensis

Neale, D. B. & Kremer, A. Forest tree genomics: growing resources and applications. Nat. Rev. Genet. 12, 111–122 (2011). CAS  PubMed  Google Scholar  Qin, P. et al. Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations. Cell 184, 3542–3558.e16 (2021). CAS  PubMed  Google Scholar  Zhou, Y. et al. Graph pangenome captures missing …

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Subgenome dominance shapes novel gene evolution in the decaploid pitcher plant Nepenthes gracilis

Subgenome dominance shapes novel gene evolution in the decaploid pitcher plant Nepenthes gracilis

Soltis, D. E. et al. Polyploidy and angiosperm diversification. Am. J. Bot. 96, 336–348 (2009). Article  PubMed  Google Scholar  Van de Peer, Y., Mizrachi, E. & Marchal, K. The evolutionary significance of polyploidy. Nat. Rev. Genet. 18, 411–424 (2017). Article  PubMed  Google Scholar  Amborella Genome Project et al. The Amborella genome and the evolution of …

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Pan-cancer landscape of epigenetic factor expression predicts tumor outcome

Pan-cancer landscape of epigenetic factor expression predicts tumor outcome

Tumors from 24 adult tissue types separate into two distinct clusters based on expression of epifactor genes We investigated whether tumors from each of the 24 adult cancer types in the TCGA repository (Fig. 1a and Supplementary Data 1)16 would separate into well-defined subgroups based on the expression patterns of 720 epifactor genes from the Epifactors database23 …

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Recombination triggers fungal crop disease

Recombination triggers fungal crop disease

Kück, U. & Pöggeler, S. Fungal Biol. Rev. 23, 86–90 (2009). Article  Google Scholar  Seidl, M. F. & Thomma, B. P. H. J. BioEssays 36, 335–345 (2014). Article  PubMed  PubMed Central  Google Scholar  Zaffaroni, M., Rimbaud, L., Rey, J.-F., Papaïx, J. & Fabre, F. Preprint at bioRxiv, https://doi.org/10.1101/2023.02.02.526796 (2023). Zeigler, R. S. Annu. Rev. Phytopathol. …

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Genesis Therapeutics Rakes In $200M For AI-Powered Drug Discovery

Genesis Therapeutics Rakes In 0M For AI-Powered Drug Discovery

Several startups focused on AI-powered drug discovery have closed multi-million-dollar funding rounds this year, including Causaly, BenchSci, Iktos, TandemAI and Protai. Another one joined the list on Monday.  Genesis Therapeutics announced the close of a $200 million Series B funding round, taking the Burlingame, California-based company’s total funding to date to more than $280 million. …

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