CGRP antagonists and dietary changes show promise for migraine treatment

CGRP antagonists and dietary changes show promise for migraine treatment

In a recent article published in the journal Medicina, researchers review advancements in migraine therapy, specifically the classification of the disease and the clinical and diet intervention advancements aimed at significantly reducing the frequency, pain, and severity of attacks. They highlight progress in calcitonin gene-related peptide (CGRP) research and the role of CGRP antagonists in …

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Treatment Choices for Atopic Dermatitis

Treatment Choices for Atopic Dermatitis

This transcript has been edited for clarity. Steven R. Feldman, MD, PhD: Hi. I’m Dr Steve Feldman, professor of dermatology at the Wake Forest University School of Medicine in Winston-Salem, North Carolina. Peter Lio, MD: And I’m Dr Peter Lio. I’m a clinical assistant professor of dermatology and pediatrics at Northwestern University Feinberg School of …

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Impressive Bleeding Profile With Factor XI Inhibitor in AF

Impressive Bleeding Profile With Factor XI Inhibitor in AF

xFurther details from the phase 2b AZALEA trial with the factor XI inhibitor abelacimab (Anthos) show significant reductions in major and clinically relevant nonmajor bleeding compared with rivaroxaban for patients with AF; the risk of stroke was moderate to high. The trial was stopped earlier this year because of an “overwhelming” reduction in bleeding with …

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IL-6R blockade reduces neonatal mortality

IL-6R blockade reduces neonatal mortality

In a recent study published in eBioMedicine, researchers from the United States of America (USA) analyzed human data to investigate the role of interleukin (IL)-6 and IL-1α in sterile intraamniotic inflammation (SIAI), a condition associated with preterm birth (PTB). Further, they examined the effect of anti-IL-6 receptor monoclonal antibody (aIL-6R) in preventing preterm births and …

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