Credit: Kateryna Kon / Science Photo Library / Getty Images A second patient with HIV has been cured with a stem cell transplant at Charité – Berlin University Medicine. In 2008, the “Berlin Patient” became the first person in the world to be cured of HIV, by such a transplant. In both cases the patients …
Credit: humonia / iStock / Getty Images Plus Genetic variants of a specific small nuclear RNA (snRNA), a family of non-coding RNAs that play a vital role in the spliceosome, account for nearly one in every twenty cases of neurodevelopmental disorders. According to early-access research published in Nature, these variants in the U4 snRNA RNU4-2 …
Credit: Dr_Microbe/Getty Images Investigators at Stanford University have discovered the role of cell stiffness and the chemical makeup of pancreatic cancer tissue has in its resistance to chemotherapy. The research, published in Nature Materials, suggests that treatment resistance can be reversed and has uncovered new potential therapeutic targets to do this. “We found that stiffer …
Forget about locating molecules in the blink of an eye, which takes as long as a quarter second—far too long a time to distinguish a sequence of subcellular events. Instead, try doing what Stanford University scientists did in a study of viral organelle formation. They located molecules in the blink of a fluorescent label. More …
Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential therapeutic for osteoporosis and other disorders that feature bone loss, and offer distinct advantages compared with existing drugs. PEPITEM was first identified in 2015 by University of Birmingham researchers. The …
Indian Institute of Technology (IIT) Madras is collaborating with Vellon Space, an Indian space startup, to advance extra-terrestrial manufacturing research and development. Officials at both organizations view the collaboration as a significant milestone in orbital microgravity research. Vellon Space will receive technology development funding from IIT Madras to demonstrate its miniature space laboratory (AsteriX Lab) …
A new study by researchers from the Wellcome Sanger Institute, the Olivia Newton-John Cancer Research Institute in Australia, and collaborators, have identified specific strains of bacteria that are linked with a positive response to combination immunotherapy in the largest study of its kind. The study is published in Nature Medicine in an article titled, “A …
Scientists say they have developed a “self-driving” lab that uses artificial intelligence (AI) and automated systems to provide in-depth analyses of catalytic reactions used in chemical research and pharmaceutical manufacturing. The new tool, called Fast-Cat, can provide more information in five days than is possible in six months of conventional testing, claim the researchers, who …
Credit: haydenbird / Getty Images Researchers at Stanford Medicine developed a new artificial intelligence model that in tests was found to be more than 90% successful at determining whether MRI scans of human brain activity were from a man or from a woman. “A key motivation for this study is that sex plays a crucial …
An innovative method known as ONCOTECH has been developed by researchers to physically attach oncolytic adenoviruses to T-cell surfaces through the interaction of antigens and receptors. To accomplish this, the viruses, which encode a Cas9 system targeting immune checkpoint inhibitor genes, are encased in cell membranes that bear T-cell-specific antigens and delivered intravenously into tumors. …